The authors report a case of a 4-year-old girl with headache, irritability, otorrhea, and unilateral exophthalmus. Computed tomography and plain films showed large lytic areas in the vault and base of the skull. No other bones were involved. The diagnosis of histiocytosis X (Hand-Schuller-Christian disease) was confirmed by bone marrow biopsy. This paper presents the cytological and radiological findings of this patient as well as a review of the literature.
Keywords: Histiocytosis, Histiocytosis X, Hand-Schuller-Christian, Skull
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